China (Mainland)
Professional Supplier of Meldrum's Acid used in Pharmaceutical Intermediate CAS NO.2033-24-1
- FOB Price: USD: 20.00-30.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Available Specifications:
1(1-1000)Kilogram1(1000-2000)Metric Ton
- Product Details
Keywords
- Meldrum's Acid
- 2,2-Dimethyl-1,3-Dioxane-4,6-Dione
- Isopropylidene malonate
Quick Details
- ProName: Professional Supplier of Meldrum's Aci...
- CasNo: 2033-24-1
- Molecular Formula: C6H8O4
- Appearance: White crystalline powder
- Application: Used in pharmaceutical intermediates a...
- DeliveryTime: Delivery on schedule
- PackAge: 25kg/barrel or as buyer’s request
- Port: Shanghai, Tianjin, Qingdao，etc.
- ProductionCapacity: 110 Metric Ton/Month
- Purity: 99%
- Storage: Normal temperature
- Transportation: By Sea, By Airport, By Express
- LimitNum: 1 Kilogram
Superiority
Best Service，High Quality and Reasonable Price
Xinxiang Juyuan Biological Technology Co., Ltd. is specialized in the manufacture, research and development of pharmaceutical intermediates and fine chemicals, such as Biapenem, and series intermediates of Penem.
The company is armed with top-notch technicians, advanced production equipments and testing instruments as well as perfect Q.C. system. Products are sold not only around China, but also to Europe and the US as well as the Asia-Pacific Region.
Details
| Brief Introduction | |
| Name | Meldrum's Acid |
| Synonyms | 2,2-Dimethyl-1,3-Dioxane-4,6-Dione |
| Isopropylidene malonate | |
| Malonic acid cyclic isopropylidene ester | |
| Cyclic isopropylidene malonate | |
| CAS | 2033-24-1 |
| EINECS | 217-992-8 |
| Molecular Formula | C6H8O4 |
| Molecular weight | 144.13 |
| Pureness | ≥99% |
| Production Capacity | 130tons/month |
| Properties | |
| Density | 1.1311 (rough estimate) |
| Melting Point | 92-96°C(lit.) |
| Boling Point | 182.71°C (rough estimate) |
| Flash Point | 150.1°C |
| Water Solubility | 2.5 g/100 mL (20 ºC) |
| Vapor Presure | 0.044-133Pa at 25℃ |
| Appearance | White crystalline powder |
| Merck | 145817 |
| BRN | 117310 |
| pKa | 5.1(at 25℃) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4434 (estimate) |
| MDL | MFCD00006638 |
| InChI | InChI=1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3 |
| InChIKey | GXHFUVWIGNLZSC-UHFFFAOYSA-N |
Application
1. It's used as a pharmaceutical intermediate. The ring (sub) isopropyl malonate can be used as an intermediate in pharmaceutical synthesis, and it can be used to prepare the compound 3-oxo-4-phenylvalerate Ethyl, further preparation of 3, 4-disubstituted-6-phenylethylpyridinone HIV-1 reverse transcriptase inhibitors.
2. It's used in organic synthesis.The protective reagent is obtained by aldol condensation and reduction with triethylamine formaldehyde. the benzyl substituted michele acid is hydrolyzed, lost CO2 and chlorosulfonic acid for Friedel-Crafts cyclization to produce 2, 3-dihydro-2-indanone. Accelerate the Noven Gall concentration reaction between aldehyde and Michaelis acid in ionic liquid (Knoevenagel condensations).
Packaging & Transport
Payment
Company Profile
Xinxiang Juyuan Biological Technology Co., Ltd. is specialized in the manufacture, research and development of pharmaceutical intermediates and fine chemicals, such as Biapenem, and series intermediates of Penem.
The company is located in the economic development zone in Xinxiang City, Henan Province, enjoying a superior location and convenient transportation.
The company is armed with top-notch technicians, advanced production equipments and testing instruments as well as perfect Q.C. system. Products are sold not only around China, but also to Europe and the US as well as the Asia-Pacific Region.
Upholding the Strategic Policy of "Survive through Quality, Develop through Technology", we sincerely welcome the cooperation of friends from all walks of life for a bright future.
FAQ:
Q1:Will you supply samples for testing
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.
Q2:What's your MOQ
A: Our MOQ starts from 1kg.
Q3:Which kind of payment terms do you accept
A: Payment by LC, T/T, D/P, PayPal, , Small-amount payment
Q4:How about your delivery time
A: Generally, it will take 3 to 5 days after receiving your advance payment.
Q5. Are you manufacturer or trade company
We are a comprehensive technology enterprise that focuses on the production and research and development of intermediates and fine chemicals.